Latest News:  

English>>Life & Culture

Epilepsy treatment drug use during pregnancy ups baby's autism risk study


08:51, April 25, 2013

WASHINGTON, April 24 (Xinhua) -- The use of valproate, an anticonvulsant drug used to treat epilepsy, during pregnancy has proven to be associated with a significantly increased risk of autism in offspring, according to a study published Wednesday in the Journal of the American Medical Association.

Valproate has previously been linked to increased risk in congenital malformations and delayed cognitive development, but little is known about the risk of other serious neuropsychiatric disorders.

Researchers with the Aarhus University Hospital in Denmark focused their research on 665,615 babies born between 1996 and 2006. The average age of the children at the end of follow-up was 8.8 years. During the study period, 5,437 children were diagnosed with autism spectrum disorder, including 2,067 with childhood autism.

The researchers identified mothers of 2,644 children exposed to antiepileptic drugs during pregnancy, including 508 exposed to valproate. They concluded that valproate was associated with an absolute risk of 4.42 percent for autism spectrum disorder and 2. 50 percent for childhood autism, compared with a total risk of 1. 53 percent for autism spectrum disorder and of 0.48 percent for childhood autism.

"For women of childbearing potential who use antiepileptic medications, these findings must be balanced against the treatment benefits for women who require valproate for epilepsy control," the researchers wrote.

We recommend:

Zhang Yuqi, Wang Quanan get married

Super kittens that make you laugh

Never-seen photos of Madonna on display

"Low-carbon fashion" show held in China

Hold on to the last tattoo of Li people

11 most creative elevators in the world

World's most precious diamonds

Cute baby and his little bulldogs

Angelababy poses for VOGUE magazine

Email|Print|Comments(Editor:YeXin、Chen Lidan)

Leave your comment0 comments

  1. Name


Selections for you

  1. China's aircraft carrier at Qingdao home base

  2. Powered parachutes used in quake rescue operations

  3. France allows same-sex marriage, adoption

  4. Are vaccines safe for your baby?

  5. Touching love stories in the quake

  6. Daily life of quake-affected people

  7. China motor fashion show debuts in Beijing

  8. WAGs of snooker players

  9. Entrepreneurs see potential in market

  10. No new stimulus needed as economy remains stable

Most Popular


  1. Insisting on wrong road, Japan has no future
  2. US 'turns blind eye to human rights'
  3. Are cities expanding too fast and too soon?
  4. Homework, games limit kids' reading
  5. Commentary: Quake-hit China grows in pain
  6. Loan guidance is good for banks, report says
  7. IMF should act responsibly
  8. Terrorist attacks should not be regionally labeled
  9. Texas town: like whipped by powerful tornado
  10. High land premiums set to affect profits

What’s happening in China

Photo story: 'Grassroots philanthropist' donates foods to quake zone

  1. Man, dead for months, found in apartment
  2. Truck driver's organs save five lives in Wuhan
  3. Suspected food poisoning kills 1, sickens 20
  4. Suicide woman got stuck in a well
  5. 2 dead in Gansu coal mine blast