U.S. starts trial to evaluate antiviral in adults hospitalized with COVID-19
A man wearing a face mask is seen on a street in Washington, D.C., the United States, on Dec. 16, 2022. (Photo by Ting Shen/Xinhua)
The trial is assessing whether S-217622 can improve clinical outcomes for patients who are hospitalized for management of COVID-19 as compared to a placebo.
LOS ANGELES, Feb. 15 (Xinhua) -- The U.S. National Institutes of Health (NIH) has initiated a multi-site clinical trial evaluating an investigational antiviral for the treatment of COVID-19, the agency announced on Wednesday.
The therapeutic, known as S-217622 or ensitrelvir fumaric acid, was discovered by Hokkaido University of Japan; and Shionogi &Co., Ltd., a Japanese pharmaceutical company.
The trial is assessing whether S-217622 can improve clinical outcomes for patients who are hospitalized for management of COVID-19 as compared to a placebo. It will enroll approximately 1,500 people at sites worldwide.
S-217622 is the first agent to be evaluated in a new global, adaptive clinical research protocol known as Strategies and Treatments for Respiratory Infections &Viral Emergencies (STRIVE), according to the NIH.
"We hope results from this trial can be applied to improve the standard of care for people with COVID-19, which still causes hundreds of deaths each day in the United States, as well as to strengthen our pandemic preparedness," said H. Clifford Lane, deputy director for Clinical Research and Special Projects at the U.S. National Institute of Allergy and Infectious Diseases.
"The STRIVE protocol and clinical research infrastructure can be adapted to evaluate additional agents for COVID-19, as well as therapeutics for other respiratory pathogens," he said.
Photos
Related Stories
- Ohio derailment leads to long-term environmental, health, legal concerns
- Interview: Report on U.S. involvement in Nord Stream explosions fits 11 known facts, says U.S. scholar
- Former U.S. Ambassador to UN Nikki Haley announces 2024 presidential bid
- Half COVID hospitalized adults in U.S. have lingering symptoms months after being discharged: study
- South Dakota tribe sues U.S. over crime: ABC News
Copyright © 2023 People's Daily Online. All Rights Reserved.