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Lefkowitz, Kobilka share 2012 Nobel Prize in Chemistry

(Xinhua)

08:26, October 11, 2012

Scientists Robert J. Lefkowitz (L) and Brian K. Kobilka (R) are introduced in Stockholm, capital of Sweden, on Oct. 10, 2012. Robert J. Lefkowitz and Brian K. Kobilka, both from universities in the United States, won the 2012 Nobel Prize in Chemistry, announced Staffan Normark, Permanent Secretary of Royal Swedish Academy of Sciences on Wednesday. (Xinhua/Liu Yinan)

STOCKHOLM, Oct. 10 (Xinhua) -- Two American scientists Robert J. Lefkowitz and Brian K. Kobilka won the 2012 Nobel Prize in Chemistry, announced Staffan Normark, Permanent Secretary of the Royal Swedish Academy of Sciences in Stockholm on Wednesday.

They were awarded "for groundbreaking discoveries that reveal the inner workings of an important family of such receptors: G-protein-coupled receptors," said the academy in a statement, adding that the studies by Lefkowitz and Kobilka are crucial for understanding how G-protein-coupled receptors function.

About a thousand genes code for such receptors, for example, for light, flavor, odor, adrenalin, dopamine and serotonin and about half of all medications achieve their effect through G-protein-coupled receptors, the statement explained.

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