Children of older dads face higher risk of non-Hodgkin's lymphoma

15:42, June 10, 2010      

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Children born to older fathers face greater risk of non-Hodgkin's lymphoma, a new study suggests.

The study, based on data of 110,999 California women, found that those born to fathers older than 40 had a 59 percent greater risk of non-Hodgkin's lymphoma than those born to fathers younger than 25.

The study, released Wednesday on the Web site of American Journal of Epidemiology, is one of the first researches to examine the link between parents' age and their adult children's risk of non-Hodgkin's lymphoma, a cancer of the blood and immune system.

As men get old, they may accumulate mutations in their reproductive cells, which increases the risk of abnormalities being passed on to children, according to study conducted by researchers at the City of Hope research and treatment center in Duarte, Los Angeles.

The findings add to the growing evidence that a father's age may have a significant effect on a child's health, said study author Yani Lu, a researcher with the center.

For example, other studies have found that children of older fathers may be more likely to develop prostate and breast cancers in adulthood, as well as some types of blood cancers during childhood.

"As a man, you may think, 'I can have a baby at 50 or 60 and live long enough to see him go through college.' But there may be other risks for your child down the line, and you may want to be conscious of those risks," Lu said.

Previous research has shown that older pregnant women are at higher risk for miscarriage and more likely to have babies with low birth weight, autism or serious health problems such as Down syndrome.

Source: Xinhua


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