British PM visits China
Text Version
RSS Feeds
Home Forum Photos Features Newsletter Archive Employment
About US Help Site Map
SEARCH   About US FAQ Site Map Site News
  -Text Version
  -RSS Feeds
  -News Archive
  -Give us feedback
  -Voices of Readers
  -Online community
  -China Biz info
  What's new
New treatment may free transplant patients from drugs
+ -
15:59, January 24, 2008

 Related News
 Everyone must be an organ donor: top doctor
 Romanian doctors find anesthetics' positive role in organ transplant
 Beijing approves 13 hospitals for organ transplant surgery
 Comment  Tell A Friend
 Print Format  Save Article
Doctors now say they have developed a technique that could free many organ transplant patients from having to take immune system suppressing drugs for the rest of their lives.

The treatment involves weakening the patient's immune system, then giving the recipient bone marrow from the person who donated the organ. In one experiment, four of five kidney recipients were off immune-suppressing medicines up to five years later.

"There's reason to hope these patients will be off drugs for the rest of their lives," said Dr. David Sachs of Massachusetts General Hospital in Boston, who led the research published in Thursday's New England Journal of Medicine.

Since the world's first transplant more than 50 years ago, scientists have searched for ways to fool the body into accepting a foreign organ as its own. Immune-suppressing drugs that prevent organ rejection came into wide use in the 1980s. But they raise the risk of cancer, kidney failure and many other problems. They also have unwanted side effects such as excessive hair growth, bloating and tremors.

Eliminating the need for anti-rejection drugs is "a huge advance," said Dr. Suzanne Ildstad, a University of Louisville immunology specialist who had no role in the work.

"It still needs some fine-tuning so that everyone who gets treated gets the same consistent outcome ... It's not the holy grail of tolerance yet," she cautioned.

In the 1990s, Sachs showed the treatment could work in a kidney recipient who was a good genetic match. The woman, who had an organ and marrow transplant in 1998, has not needed anti-rejection drugs for a decade.

The new study involved five people who got kidneys from parents or siblings who had slightly different tissue types from the patients. Since many kidney transplants are similarly mismatched, there is hope more people might one day be spared immune-suppressing drugs.


  Your Message:   Most Commented:

|About | Advertise on site | Contact us | Site map | Job offer|
Copyright by People's Daily Online, All Rights Reserved