Several people were shot at Northern Illinois University in the Chicago suburb of DeKalb, Ill. Thursday, CNN reported.
The shooting took place shortly after 3 p.m. (2100 GMT), when police received report that a white, male shooter with a shotgun and pistol opened fire in a lecture hall of the university.
The gunman is now dead, according to DeKalb police.
Meanwhile, a local hospital said it expects to receive 15 patients and have so far treated at least two.
The university has posted a campus alert on its web site and canceled classes for Thursday night.
Witnesses said several wounded people were took out on stretchers.
DeKalb is 102 km west of downtown Chicago and there are some 25,000 students in the campus Northern Illinois University.